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GLP-1 physiology in obesity and development of incretin-based drugs for chronic weight management

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Bimekizuma … Continue reading "Bimekizumab-bkzx Therapeutic Cheat Sheet" Roflumilast Therapeutic Cheat Sheet Roflumilast is a non-steroidal topical cream that was FDA approved for the treatment of plaque psoriasis in 2022.1 Roflumilast selectively inhibits phosphodiesterase-4 (PDE-4), which is an enzyme that mediates inflammatory responses and has been shown to play a role in several dermatologic diseases.2 Prior to topical roflumilast, oral PDE-4 inhibitors have been investigated across a wide variety o … Continue reading "Roflumilast Therapeutic Cheat Sheet" Apremilast Therapeutic Cheat Sheet Apremilast (OTEZLA®) is a twice daily oral medication that is FDA approved for adults with plaque psoriasis, psoriatic arthritis and oral ulcers associated with Behçet’s Disease.1 This drug is being extended as an off-label treatment to target inflammation in a number of different conditions