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Starting tirzepatide at maintenance dose (10 mg or 15 mg) causes severe nausea and vomiting in approximately 60% of patients (SURMOUNT-1 trial, Jastreboff et al., NEJM, 2022)
barimelts051
Intra EAA Flavour:90's Pick 'n' Mix
In a small sample of male patients, resting-state data also showed that co-administration of intragastric glucose and GLP-1 antagonist resulted in higher resting state functional connectivity (rsFC) between the hypothalamus and the left lateral orbitofrontal cortex (OFC), between the right NAc and the right lateral OF, and lower rsFC between the midbrain and the right caudate nucleus
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