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The change of aldosterone concentration was significantly larger after liraglutide than after placebo only in patients with eGFR 60 ml/min/1.73 m 2 , (− 7.3) [95%CI (− 11.7)–(− 0.2)] and (− 0.3) [95%CI (− 2.2)–(3.8)] respectively, ( p = 0.007)