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Weight loss drug semaglutide approved for NHS use - BBC News

We consider a “normal” or acceptable range of PCR between 0.5 and 2, while countries with a PCR index greater than 10 are, with a high degree of certainty, substantially underrepresented in the development of novel pharmaceuticals, and thus potentially consuming medications in development for which patients with similar ethnic or cultural 1 profiles have not been adequately represented

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Among other host factors, this balance between energy intake and expenditure relies on the microorganisms and their metabolites, helping in nutrient processing, nutrient access regulation, and storage in the body by secreting hormones and mediators of energy homeostasis (3)