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Other findings have also suggested that semaglutide might play a role in protecting, or potentially even promoting, cartilage health, bolstering the cushioning tissue within your knee joint

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Specifically, the GLP-1RA semaglutide may have increased pharmacological activity for weight loss compared to exenatide [142, 143], and semaglutide was recently approved for the treatment of obesity in adolescents 12 years and older, with a 17% decrease in BMI with semaglutide compared with placebo [100]