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Dose:10.00 mg
After 1-year follow-up, the mean reduction in A1C was significantly greater in the biphasic (1.3%) and prandial groups (1.4%) than in the basal group (0.8%).[144] However, after 3 years, basal or prandial insulin-based regimen had better A1C control than biphasic insulin-based regimen.[145] Safety tolerability and body weight The combination of insulin and SU results in a reduction of necessary insulin dose per day.[60,138] However, most studies adding SUs to insulin reported milder hypoglycemic episodes versus insulin monotherapy (range: 2.2–6.1 vs
