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Do I need a ‘washout’ period if I switch from Semaglutide to Tirzepatide
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The problem was the side effects associated, particularly with GLP-1, are what we call peak to trough: so the difference between the highest amount of drug and the lowest and then going back up again to the highest caused by this twice-a-day dosing—which you can imagine someone bouncing around maybe two to three times, the drug at peak, then trough, causes a lot of GI distress
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