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Although proposed mechanisms—such as modulation of the HPA axis and central GLP‐1 receptor signalling—suggest potential antidepressant effects, clinical findings remain inconsistent
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“I don’t know if it’s in my head or if it really is something that’s helping, but I’m not going to stop wearing them.” Hargens, the 34-year-old who’s long struggled with her weight, is similarly unbothered by the concept of her experience with the patches being chalked up to the placebo effect
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