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Consistent with these findings, a recent clinical pilot study further demonstrated that liraglutide not only promoted weight reduction and improved glycemic control in patients with obesity and T2D, but also induced significant shifts in gut microbial composition (α and β diversity) and metabolic pathways, reinforcing the concept that microbiota modulation may contribute to the therapeutic effects of GLP-1 RAs (42)

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In collaboration with Australian Border Force (ABF), the TGA is now laboratory testing the pens, but warned that the safety, quality, and efficacy of these products remains unknown