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Patients on the twice-daily exenatide were significantly less likely to experience treatment failure than those on the sulfonylurea glimepiride (41% versus 54%, HR 0.75, 95% CI 0.62 to 0.90,P=0.002), Baptist Gallwitz, MD, of Universitatsklinikum Tubingen in Tubingen, Germany, and colleagues reported online in The Lancet and at the American Diabetes Association meeting here
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