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Furthermore, while we and others previously showed that GIPR agonism decreases body weight and food intake via Gip r signalling in GABAergic neurons 14,19 , here we found that the ability of GIPR antagonism to amplify GLP-1-induced weight loss does not depend on the presence of GIPR in GABAergic neurons
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Research has raised concerns about certain active ingredients in popular GLP-1 medications, including liraglutide (the compound used in Saxenda and Victoza) and semaglutide (the active ingredient in Ozempic and Wegovy)
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