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Xueying Lin and colleagues established a zebrafish ADPKD model by transcription activator-like effector nucleases (TALEN) mediated gene editing to study the effect of autophagy in ADPKD which is directly controlled by the mTOR energy sensing and proliferative pathways

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Additionally, GLP-1 medications are generally well tolerated, with minimal psychiatric side effects compared to traditional antidepressants or anti-addiction medications